Biomarker-guided immunosuppression following kidney transplantation successfully tested
Biomarker-guided immunosuppression following kidney transplantation successfully tested
International study coordinated by MedUni Vienna demonstrates safety of a new approach to more personalised dosing of immunosuppressive drugs. First results of our study have recently been presented during the European Renal Association (ERA) conference in Glasgow on June 4, 2026. A scientific publication will follow within the next couple of months. We are currently still working on some final analyses.
An international research team coordinated by the Medical University of Vienna has demonstrated in a clinical trial that Torque-Teno-virus-guided dosing of immunosuppressants in kidney transplant recipients is safe. The results of the TTVguideIT study, recently being presented at the annual congress of the European Society of Nephrology, suggest that immunosuppressive therapy could be further personalised and reduced in certain patient groups in the future. The study forms the central conclusion of the EU project TTVguideTX, which was coordinated by Gregor Bond from the Division of Nephrology and Dialysis at the Department of Medicine III at MedUni Vienna.
Further information can be found via the official Medical University Vienna.
About TTVguideTX
TTVguideTX was a research project funded by the European Union under Horizon 2020 to develop and clinically trial a new tool for managing immunosuppression following kidney transplantation. The approach is based on measuring Torque-Teno-virus in the blood. The aim was to better assess the balance between adequate protection against organ rejection and the lowest possible risk of infection.
More info available on the website
Final TTVguideTX outreach event, October 9, 2026, Vienna
After nearly six years of work, we are closing the project with a public (hybrid) session. Clinicians, researchers, transplant patients and patient organisations, and anyone curious about the project, are warmly invited to join.
