Trials of Excellence in Southern Africa III

Funding programme: European & Developing Countries Clinical Trials Partnership Association  (N CSA2022NoE-3105)

Coordinator: Fundaçao Manhiça (FM-CISM)

Budget: €5M

Duration: 3 years (Sep 2021 - Aug 2024)

With TESA III, 15 institutions from 9 African and 3 European countries come together to strengthen and enhance the capacities for clinical research in Southern Africa built during TESA, and to strengthen the collaboration of North-South and South-South networking activities among its members.

To achieve this, TESA III focuses on transfering technology, strengthening the capacities among partner sites in Southern Africa, promoting professional development and scientific leadership and fostering collaborations to maximize impact. TESA develops specific activities aiming to increase researchers critical mass devoted to health, develop first-class institutions engaging clinical trials to prevent poverty-related diseases and promote dialogue between researchers, communities and policymakers


  1. To promote and consolidate the TESA network activities across the region and to involve other countries which are not yet part of the network.
  2. To use the established regional reference laboratories and joint clinical trials for on-the-job training in Malaria, HIV/AIDS and Tuberculosis, and promote basic studies for the LDS to engage in hands on training at their sites and, also to provide a financial support for some infrastructure upgrades.
  3. To establish and promote capacity building built from TESA II, including data management, data and analysis and data sharing across the network.
  4. To establish a joint platform with national and regional agencies to develop and straightening collaboration on evidence sharing for the decision-making process, dialogue between researchers, communities, and policy-makers to maximize the impact of clinical research in Africa.